This research area deals with the development and optimization of drugs, their optimal delivery and maintenance at their sites of action as well as with the molecular diagnostics of human diseases.
The study of physicochemical properties of drugs and interactions with their targets, the development of drug formulations, new materials and strategies for design and controlled delivery of drugs to enhance therapeutic activity, targeted radiotherapeutic agents and molecular imaging agents, are examples of areas under investigation. Activities also include the study of drug transport mechanisms across biological barriers as well as the study of their absorption, distribution, metabolism and elimination, which are important determinants of their biologic activity. The development of new nanomaterials, synthetic biology approaches for disease diagnostic applications, biological therapeutics including viral vector-mediated gene therapy, and the delivery of precision medicine are emerging topics of interest.
Investigators
Research News
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University of Toronto scientists appointed as GSK chairs will advance drug delivery research and vaccine education tools for healthcare professionals
The University of Toronto’s Leslie Dan Faculty of Pharmacy has announced the appointments of two leading scientists as endowed GSK research chairs.
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Start-up launched at Leslie Dan Faculty of Pharmacy earns second place in biotech pitch competition
Re:Pair Genomics receives $10,000 prize to develop key component of gene therapy.
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What can professional regulators do about society’s biggest problems?
Professor Zubin Austin explores role of regulators in tackling challenging issues, such as climate change.
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