In this area our teams are elucidating the biochemical and cellular basis of human diseases and the molecular mechanisms underlying drug action and their targets.
Our investigation of disease mechanisms provides insights into identification of novel therapeutic targets for which small molecules or biologics are being developed. Research is directed towards the molecular and cellular mechanisms underlying the function of therapeutic targets, correcting the target using gene therapy, and the intracellular signalling pathways they control and the mechanistic study of drug action. Approaches incorporate human studies, patient-derived samples and animal models of disease. Our research teams are interested in several human diseases or conditions including drug addiction, autism, diabetes, cancer, genetic disorders, infectious diseases, and neurological diseases.
Alison Thompson’s media expert and provincial advisory roles contribute to public discussions about challenging topics during COVID-19 pandemic.Read More
Two professors at the U of T’s Leslie Dan Faculty of Pharmacy have been elected as fellows to the Canadian Academy of Health Sciences (CAHS).Read More
Professor Shana Kelley is among nine professors from across the University of Toronto appointed as Fellows to the Royal Society of Canada.Read More