In this area our teams are elucidating the biochemical and cellular basis of human diseases and the molecular mechanisms underlying drug action and their targets.

Our investigation of disease mechanisms provides insights into identification of novel therapeutic targets for which small molecules or biologics are being developed. Research is directed towards the molecular and cellular mechanisms underlying the function of therapeutic targets, correcting the target using gene therapy, and the intracellular signalling pathways they control and the mechanistic study of drug action. Approaches incorporate human studies, patient-derived samples and animal models of disease. Our research teams are interested in several human diseases or conditions including drug addiction, autism, diabetes, cancer, genetic disorders, infectious diseases, and neurological diseases.

Investigators

Research News

Pharmacists on the frontline of pain care

Whether they are helping patients manage pain during a COVID-19 vaccination, compounding children’s doses of pain medication during a nation-wide shortage or checking for drug interactions for patients with chronic pain, pharmacists are on the frontlines of providing pain care.
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