In this area our teams are elucidating the biochemical and cellular basis of human diseases and the molecular mechanisms underlying drug action and their targets.
Our investigation of disease mechanisms provides insights into identification of novel therapeutic targets for which small molecules or biologics are being developed. Research is directed towards the molecular and cellular mechanisms underlying the function of therapeutic targets, correcting the target using gene therapy, and the intracellular signalling pathways they control and the mechanistic study of drug action. Approaches incorporate human studies, patient-derived samples and animal models of disease. Our research teams are interested in several human diseases or conditions including drug addiction, autism, diabetes, cancer, genetic disorders, infectious diseases, and neurological diseases.
Investigators
Research News
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University of Toronto scientists appointed as GSK chairs will advance drug delivery research and vaccine education tools for healthcare professionals
The University of Toronto’s Leslie Dan Faculty of Pharmacy has announced the appointments of two leading scientists as endowed GSK research chairs.
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Start-up launched at Leslie Dan Faculty of Pharmacy earns second place in biotech pitch competition
Re:Pair Genomics receives $10,000 prize to develop key component of gene therapy.
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What can professional regulators do about society’s biggest problems?
Professor Zubin Austin explores role of regulators in tackling challenging issues, such as climate change.
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