In this area our teams are elucidating the biochemical and cellular basis of human diseases and the molecular mechanisms underlying drug action and their targets.
Our investigation of disease mechanisms provides insights into identification of novel therapeutic targets for which small molecules or biologics are being developed. Research is directed towards the molecular and cellular mechanisms underlying the function of therapeutic targets, correcting the target using gene therapy, and the intracellular signalling pathways they control and the mechanistic study of drug action. Approaches incorporate human studies, patient-derived samples and animal models of disease. Our research teams are interested in several human diseases or conditions including drug addiction, autism, diabetes, cancer, genetic disorders, infectious diseases, and neurological diseases.
Investigators
Research News
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U of T researchers target neurogenesis in new approach to treat Parkinson’s disease
Researchers at the Temerty Faculty of Medicine found a way to better control the preclinical generation of key neurons depleted in Parkinson’s disease.
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High school students learn about pharmacy and pharmaceutical sciences during research exploration opportunity
Exciting week of activities showcases the potential of science-focused careers.
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University of Toronto scientists appointed as GSK chairs will advance drug delivery research and vaccine education tools for healthcare professionals
The University of Toronto’s Leslie Dan Faculty of Pharmacy has announced the appointments of two leading scientists as endowed GSK research chairs.
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