Molecular Basis for Drug Targets and Diseases
In this area, our teams are elucidating the biochemical and cellular basis of human diseases and the molecular mechanisms underlying drug action and their targets.
Our investigation of disease mechanisms provides insights into the identification of novel therapeutic targets for which small molecules or biologics are being developed. Research is directed towards the molecular and cellular mechanisms underlying the function of therapeutic targets, correcting the target using gene therapy, and the intracellular signalling pathways they control and the mechanistic study of drug action. Approaches incorporate human studies, patient-derived samples and animal models of disease.
Our research teams are interested in several human diseases or conditions, including:
- Drug addiction
- Autism
- Diabetes
- Cancer
- Genetic disorders
- Infectious diseases
- Neurological diseases
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I'm Pharmacy Podcast
S2.E1: Building the Foundation – Where do the ideas for new drugs start from? Where do they even start by inventing a new drug? And how does one find the next insulin?
Research News
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AI-powered platform accelerates discovery of new mRNA delivery materials
Self-driving LUMI-lab system combines AI and robotics to advance design and evaluation of lipid nanoparticles for mRNA delivery.
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New faculty Joseph Brown will explore how AI can accelerate peptide-based drug design
The Leslie Dan Faculty of Pharmacy welcomes Joseph S. Brown as Assistant Professor in Biomolecular Science, whose research combines chemistry, biology, and machine learning to accelerate the discovery of peptide-based therapeutics.
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How Bebe Simelane’s summer research is fueling her passion for science
Through hands-on research, mentorship, and exposure to cutting-edge tools like AI, this USRP student is gaining the skills and confidence to pursue graduate studies and advance science.
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