Since its establishment in 2000, the GSK Chair in Pharmaceutics and Drug Delivery has earned a remarkable reputation for its dedication to advancing our understanding of drug discovery and delivery. With the appointment of Bowen Li, assistant professor, Leslie Dan Faculty of Pharmacy, the chair's legacy of groundbreaking research and innovation in pharmaceutics and drug delivery is set to continue.

Working at the intersection of biomaterials sciences, drug delivery, and immunoengineering, Li leads a cutting-edge research program dedicated to building nonviral delivery systems for nucleic acids, including mRNA, circular RNA, and CRSIPR-Cas9. This rapidly evolving, highly interdisciplinary area of biomedicine is focused on tapping the potential of RNA to encode therapeutic proteins to prevent or treat multiple diseases, including cancer, infectious diseases, and genetic disorders.

The Li lab recently developed a pioneering high-throughput platform integrating combinatorial chemistry with deep learning algorithms. This innovative approach enables the swift design, synthesis, and screening of versatile delivery vehicles for customized nucleic acids, with the goal of accelerating the clinical translation of next-generation medicines.


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